Production and application of 3-phosphoadenosine-5- phosphosulfate / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 1222-1233, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-771806
ABSTRACT
Sulfated compounds are widely present in cytoplasm, on cell surface, and in extracellular matrix. These compounds play important roles in cell development, differentiation, immune response, detoxication, and cell signal transduction. 3-Phosphoadenosine-5-phosphosulfate (PAPS) is the universal sulfate group donor for the biosynthesis of sulfated compounds. Up to now, the synthesis of PAPS is still too expensive for industrial applications. This review focuses on the recent progress of PAPS production and summaries the application of PAPS, particularly in the production of glucosinolate, heparin, condroitin sulfate, and oxamniquine production.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phosphoadenosine Phosphosulfate
/
Sulfates
/
Cell Differentiation
/
Chondroitin Sulfates
/
Metabolism
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2019
Type:
Article
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