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A Case Report of Primary Pulmonary Synovial Sarcoma with Postoperative Multiple Metastases Treated with Apatinib / 中国肺癌杂志
Chinese Journal of Lung Cancer ; (12): 880-884, 2018.
Article in Chinese | WPRIM | ID: wpr-772349
Responsible library: WPRO
ABSTRACT
Primary pulmonary synovial sarcoma is a rare pulmonary malignant tumor originated from primitive mesenchymal, which has short overall survival and poor prognosis. Related case reports are lacked at home and abroad. In recent years, the development of targeted therapy has brought remarkable benefits to cancer patients. Apatinib (Hengrui Pharmaceutical Co. Ltd, Jiangsu, People's Republic of China) is a small molecule vascular endothelial growth factor receptor 2 (VEGFR-2) inhibitor, which selectively inhibits VEGFR-2 and blocks the VEGF signal pathway, then strongly inhibiting the tumor angiogenesis. Apatinib has shown favorable therapeutic effect and acceptable toxicity on various tumors. Here we report a case of primary pulmonary synovial sarcoma with postoperative multiple metastases treated with apatinib, in order to provide a new considerable treatment.
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Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Postoperative Period / Pyridines / General Surgery / Humans / Male / Sarcoma, Synovial / Therapeutic Uses / Drug Therapy / Lung Neoplasms Type of study: Case report Language: Chinese Journal: Chinese Journal of Lung Cancer Year: 2018 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Postoperative Period / Pyridines / General Surgery / Humans / Male / Sarcoma, Synovial / Therapeutic Uses / Drug Therapy / Lung Neoplasms Type of study: Case report Language: Chinese Journal: Chinese Journal of Lung Cancer Year: 2018 Type: Article