Analysis of the First Diagnosis Symptom and Its Influencing Factors in 500 Patients with Lung Cancer / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 408-412, 2018.
Article
in Zh
| WPRIM
| ID: wpr-772426
Responsible library:
WPRO
ABSTRACT
BACKGROUND@#As the morbidity and mortality in lung cancer keep raising, we are here to discuss the effect of clinical features especially the initial symptomon on diagnosis and follow-up treatment of newly diagnosed lung cancer patients.@*METHODS@#The clinical features of the 500 patients with lung cancer in our hospital from March, 2017 to May, 2017 were analyzed retrospectively, including the initial symptom, stage, biomarkers, pathology, etc. RESULTS: There were 266 famle (53.3%), 372 adenocarcinoma (74.4%), 285 smokers (58%), status score of most patients (98.2%) was 0-1. 58.2% (n=291) of all the patients got biomarkers test, of which epidermal growth factor receptor (EGFR) mutations was 61.2%(178/291), anaplasticlymphoma kinase (ALK) fusion gene positive was 4.1% (12/291). Smoking status, initial symptom, pathological typing, TNM staging and EGFR mutation were the main factors affecting follow-up treatment.@*CONCLUSIONS@#Patients with typical symptoms have shorter diagnosis time. Smoking status, lung cancer-related symptoms, pathology, TNM staging and EGFR mutation status are the main factors that affect the follow-up treatment.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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China
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Retrospective Studies
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Receptor Protein-Tyrosine Kinases
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Diagnosis
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ErbB Receptors
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Smokers
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Anaplastic Lymphoma Kinase
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Genetics
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Lung Neoplasms
Type of study:
Diagnostic_studies
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Observational_studies
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Country/Region as subject:
Asia
Language:
Zh
Journal:
Chinese Journal of Lung Cancer
Year:
2018
Type:
Article