Effects of platelet-derived growth factor on nerve regeneration around implant in rats / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 350-354, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-772648
ABSTRACT
OBJECTIVE@#To investigate the effect of platelet-derived growth factor (PDGF) on nerve regeneration in peri-implant tissues.@*METHODS@#SD rats with implants in their femurs were injected with PDGF solution. The effects of PDGF on nerve regeneration in peri-implant tissues were analyzed by immunohistochemical staining.@*RESULTS@#PDGF increased the number of nerve fibers in peri-implant tissues at early stage. PDGF had no significant effect on the number of nerve fibers in peri-implant tissues at late stage. Moreover, these nerves had a typical structure of peripheral nerve fibers.@*CONCLUSIONS@#PDGF can promote nerve regeneration in peri-implant tissues at early stage. This study provided a certain experimental basis for the clinical application of PDGF to promote nerve regeneration and further improve the sensory function of the implant.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Platelet-Derived Growth Factor
/
Dental Implants
/
Rats, Sprague-Dawley
/
Nerve Fibers
/
Nerve Regeneration
Limits:
Animals
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS