Genome Writing: Current Progress and Related Applications / 基因组蛋白质组与生物信息学报·英文版
Genomics, Proteomics & Bioinformatics
;
(4): 10-16, 2018.
Article
in English
| WPRIM
| ID: wpr-773007
ABSTRACT
The ultimate goal of synthetic biology is to build customized cells or organisms to meet specific industrial or medical needs. The most important part of the customized cell is a synthetic genome. Advanced genomic writing technologies are required to build such an artificial genome. Recently, the partially-completed synthetic yeast genome project represents a milestone in this field. In this mini review, we briefly introduce the techniques for de novo genome synthesis and genome editing. Furthermore, we summarize recent research progresses and highlight several applications in the synthetic genome field. Finally, we discuss current challenges and future prospects.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Genetic Engineering
/
Genome, Human
/
High-Throughput Nucleotide Sequencing
/
CRISPR-Cas Systems
/
Gene Editing
/
Methods
Limits:
Animals
/
Humans
Language:
English
Journal:
Genomics, Proteomics & Bioinformatics
Year:
2018
Type:
Article
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