Distribution of Telocytes in Vital Organs of ApoE Mice / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 778-784, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-774019
ABSTRACT
Objective To identify and verify the distribution of Telocytes derived from heterogeneous interstitial cells in the vital organs of ApoE mice.Methods Heart,kidney,and liver tissues were harvested from ApoE adult mice. Immunohistochemical assays were performed by using different immunobiological markers.Results Telocytes were found in these vital organs. The expressions of immunobiological markers differed among different organs. CD34,CD117,and CD28 were positively expressed in Telocytes in cardiac tissue;CD117 and plateled-derived growth factor-Α were negatively expressed in Telocytes in renal tissue;and CD117 and plateled-derived growth factor receptor-Α had negative expression in Telocytes in hepatic tissue. Furthermore,the distribution of Telocytes also differed in the same organ.Conclusions Telocytes exist in the vital organs of ApoE mice,as demonstrated by immunohistochemisty assay. The expressions of immunobiological markers differ among Telocytes in different organs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
CD28 Antigens
/
Proto-Oncogene Proteins c-kit
/
Antigens, CD34
/
Cell Biology
/
Telocytes
/
Mice, Knockout, ApoE
/
Kidney
/
Liver
/
Metabolism
/
Myocardium
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2018
Type:
Article
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