Clinical features and prognosis of neonates with nonimmune hydrops fetalis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 253-258, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-774090
ABSTRACT
OBJECTIVE@#To study the clinical features, etiology and prognosis of neonates with nonimmune hydrops fetalis (NIHF).@*METHODS@#A retrospective analysis was performed for the clinical data and outcomes of 23 neonates with NIHF.@*RESULTS@#Of the 23 neonates with NIHF, 18 (78%) were preterm infants and 5 (22%) were full-term infants; 12 (52%) had birth asphyxia (including 5 cases of severe asphyxia). As for the causes of NIHF, 8 neonates (35%) had twin-twin transfusion syndrome (TTTS), 3 (13%) had cardiovascular malformation, 3 (13%) had parvovirus B19 infection, 2 (9%) had congenital chylothorax, 1 (4%) had Turner syndrome, 1 (4%) had Coxsackie virus infection, and 5 (22%) had unknown etiology. Of the 23 neonates, 13 achieved clinical cure, 10 died, resulting in a neonatal mortality rate of 43%. Compared with the survival group, the death group had a significantly higher proportion of preterm infants or infants with asphyxia, 5-minute Apgar score<8 or heart failure (100%/100%/60%/60% vs 62%/15%/8%/8%; P<0.05).@*CONCLUSIONS@#Birth asphyxia is common in neonates with NIHF. The neonates with a lower gestational age, a more serious asphyxia or heart failure have a higher risk of death in the neonatal period. Being the recipient of TTTS is a major cause of NIHF.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Hydrops Fetalis
/
Infant Mortality
/
Retrospective Studies
/
Gestational Age
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Infant
/
Infant, Newborn
/
Pregnancy
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2019
Type:
Article
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