A comparative study of viscoelasticity between normal cornea and keratoconus / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 613-618, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-774164
ABSTRACT
Study of the mechanical properties of in vivo corneal materials is an important basis for further study of corneal physiological and pathological phenomena by means of finite element method. In this paper, the elastic coefficient ( ) and viscous coefficient ( ) of normal cornea and keratoconus under pulse pressure are calculated by using standard linear solid model with the data provided by corneal visualization scheimpflug technology. The results showed that there was a significant difference of and between normal cornea and keratoconus cornea ( < 0.05). Receiver operating characteristic curve analysis showed that the area under curve (AUC) for , and their combined indicators were 0.776, 0.895 and 0.948, respectively, which indicated that keratoconus could be predicted by and . The results of this study may provide a reference for the early diagnosis of keratoconus and avoid the occurrence of keratoconus after operation, so it has a certain clinical value.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Physiology
/
Viscosity
/
ROC Curve
/
Area Under Curve
/
Cornea
/
Elasticity
/
Keratoconus
Type of study:
Prognostic study
/
Screening study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2019
Type:
Article
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