Study on Immunophenotypes and Gene of Acute Lymphoblastic Leukemia--Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1831-1835, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-774377
ABSTRACT
Transplantation-associated thrombotic microangiopathy (TA-TMA) is one of the fatal complications of hematopoietic stem cell transplantation(HSCT). The pathogenesis of TA-TMA has not been fully elucidated. The latest researches show that the abnormal activation of the complement system may lead to widespread endothelial injury which may play an important role in the pathogenesis of this disease. Incontrotable hypertension, proteinuria, increase of soluble C5b-9 concentration and early pericardial effusion are the risk factors of TA-TMA . In this review, the latest advances of pathogenesis, early diagnosis, treatment and other aspects of the progress of TA-TMA are summarized, so as to provide new ideas to early diagnosis and treatment in TA-TMA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acute Disease
/
Immunophenotyping
/
Hematopoietic Stem Cell Transplantation
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Thrombotic Microangiopathies
Type of study:
Risk factors
/
Screening study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS