Identification of Phenotype and Genotype in One Case with Weak D blood group / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1800-1803, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-774383
ABSTRACT
OBJECTIVE@#To investigate the phenotype and genotype of the weak D blood group in one case of Chinese Han people.@*METHODS@#Phenotype of blood sample was identified with serologic tests; PCR-SBT was applied for the analysis of genotype and RhD zygosity.@*RESULTS@#Both saline and gel card tests demonstrated this case to be dCcee, which was contrary to glass bead card result. Some of the RBC D epitopes were negative.c.1022T>A allele was identified with PCR-SBT and the zygosity analysis showed this case to be D/d.@*CONCLUSION@#RHD*1022 A is more suitable to be categorized as weak partial D other than weak D in a Chinese Han people.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Rh-Hr Blood-Group System
/
Exons
/
Asian People
/
Alleles
/
Genotype
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2018
Type:
Article
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