Evaluation of Material Permeability of Type I Collagen Hydrogel / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
;
(6): 140-143, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-774488
ABSTRACT
OBJECTIVES@#To establish an experimental method for evaluating material permeability of type I collagen hydrogels.@*METHODS@#Using BSA-FITC as an indicator, by combining BSA-FITC with PBS they were used as permeability media, and using transwell load hydrogen sample to detect BSA-FITC transparent rate.@*RESULTS@#In the concentration range of 100 μg·mL~0.781 μg·mL, the standard curve ≥ 0.99, Lower Limit of Quantity (LLOQ) is 3.125 μg·mL, RSD <5%, detection recovery rate is in the range of 80%~120%.@*CONCLUSIONS@#In this study, we established an experimental method for evaluating material permeability of hydrogel. The BSA-FITC transparent rate of type I collagen hydrogel was 100% at 28 h.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Permeability
/
Materials Testing
/
Chemistry
/
Hydrogels
/
Collagen Type I
Language:
Chinese
Journal:
Chinese Journal of Medical Instrumentation
Year:
2018
Type:
Article
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