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Mesenchymal stem cell transplantation in the treatment of bronchopulmonary dysplasia: opportunities and challenges / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics ; (12): 619-623, 2019.
Article in Chinese | WPRIM | ID: wpr-775135
ABSTRACT
Bronchopulmonary dysplasia (BPD) is one of the most common chronic lung diseases in neonates especially in preterm infants. It is also the main reason leading to a poor prognosis. The prognosis of the neonates with BPD is unsatisfactory with current treatment strategies. Recent clinical trails have found that mesenchymal stem cell (MSC) transplantation might be effective and promising for treatment of BPD in neonates. This article outlines the characteristics of MSC and the potential mechanisms of MSC transplantation for BPD in vivo, and the safety and feasibility of MSC transplantation in BPD neonates, as well as the challenges in clinical trials on MSC transplantation for treatment of BPD.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Bronchopulmonary Dysplasia / Infant, Premature / Mesenchymal Stem Cell Transplantation Type of study: Prognostic study Limits: Humans Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Bronchopulmonary Dysplasia / Infant, Premature / Mesenchymal Stem Cell Transplantation Type of study: Prognostic study Limits: Humans Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2019 Type: Article