Application of mechanosensitive channels in sonogenetics / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 34-38, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-775257
ABSTRACT
As a non-invasive approach, sonogenetics is applied to control neuronal activity. The mechanosensitive channel(MSC), which has low threshold of responding to ultrasound, may be the alternative solution. Sonogenetics is the technique that activates the MSC expressed in targeted neurons by low intensity ultrasound, thus achieve the neuromodulation. In this review, we introduce the mechanosensitive channel of large conductance, transient receptor potential, channels of the two-pore-domain potassium family, Piezo and the recent progress on their application in sonogenetics.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biomechanical Phenomena
/
Ultrasonic Waves
/
Ion Channels
/
Metabolism
/
Neurons
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2019
Type:
Article
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