Research progress on and behaviors of poorly soluble Chinese materia medica nanosuspension / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3828-3833, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-775410
ABSTRACT
Nanosuspension (also called nanocrystal suspension or nanocrystal) could significantly enhance the saturated solubility and dissolution of insoluble drugs, and improve their bioavailability by reducing particle size and increasing the specific surface, which could then solve the delivery problems of the poorly soluble active ingredients and effective parts of Chinese materia medica (CMM). Based on the brief summaries of nanosuspension preparation methods, this paper would mainly review the and behaviors of poorly soluble CMM nanosuspension, discuss and analyze its problems, so as to provide reference and thinking for the further study of nanosuspension drug delivery system of poorly soluble CMM and promote the development and perfection of nanosuspension technology in CMM.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Particle Size
/
Solubility
/
Suspensions
/
Materia Medica
/
Biological Availability
/
Chemistry
/
Drug Delivery Systems
/
Nanoparticles
/
Medicine, Chinese Traditional
Type of study:
Diagnostic study
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2018
Type:
Article
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