Pericyte Plasticity in the Brain / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 551-560, 2019.
Article
in English
| WPRIM
| ID: wpr-775461
ABSTRACT
Cerebral pericytes are perivascular cells that stabilize blood vessels. Little is known about the plasticity of pericytes in the adult brain in vivo. Recently, using state-of-the-art technologies, including two-photon microscopy in combination with sophisticated Cre/loxP in vivo tracing techniques, a novel role of pericytes was revealed in vascular remodeling in the adult brain. Strikingly, after pericyte ablation, neighboring pericytes expand their processes and prevent vascular dilatation. This new knowledge provides insights into pericyte plasticity in the adult brain.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Brain
/
Brain Diseases
/
Capillaries
/
Pericytes
/
Endothelial Cells
/
Diabetic Retinopathy
/
Cellular Microenvironment
/
Vascular Remodeling
Limits:
Animals
/
Humans
Language:
English
Journal:
Neuroscience Bulletin
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS