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Advance of Research on the Immunotherapy Targeting B Cell Maration Antigen for Multiple Myeloma--Review / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 1701-1705, 2019.
Article in Chinese | WPRIM | ID: wpr-775662
ABSTRACT
Abstract  B cell maturation antigen (BCMA) is an ideal target for precise treatment due to its highly selective expression on malignant myeloma cells. This review summarizes briefly the advances in the latest research progress on biological activity of BCMA, its significance as a biomarker and immunotherapy direcited against BCMA, such as bispecific antibodies, antibody drug conjugates, chimeric antigen receptor T cell therapy against mature B cell antigens.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / B-Lymphocytes / T-Lymphocytes / Antigens, Differentiation, B-Lymphocyte / B-Cell Maturation Antigen / Immunotherapy / Multiple Myeloma Limits: Humans Language: Chinese Journal: Journal of Experimental Hematology Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / B-Lymphocytes / T-Lymphocytes / Antigens, Differentiation, B-Lymphocyte / B-Cell Maturation Antigen / Immunotherapy / Multiple Myeloma Limits: Humans Language: Chinese Journal: Journal of Experimental Hematology Year: 2019 Type: Article