Exosomes in the Pathogenesis of Rheumatoid Arthritis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 556-561, 2019.
Article
in Zh
| WPRIM
| ID: wpr-775995
Responsible library:
WPRO
ABSTRACT
Exosomes are 30-100 nm vesicles secreted from almost all types of cells.They contain various molecular constituents,including proteins,lipids,and RNA.As important mediators of cell-to-cell communication,exosomes are involved in a variety of physiological and pathological processes such as inflammatory reaction,cell proliferation and differentiation,tissue repair,immune signal transduction,and stress response.Exosomes can regulate and maintain the initiation and progression of many autoimmune diseases,especially rheumatoid arthritis.Meanwhile,exosomes may be a new biomarker for the diagnosis of rheumatoid arthritis and a potential treatment vector for this disease.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Arthritis, Rheumatoid
/
Signal Transduction
/
Cell Communication
/
Exosomes
Type of study:
Etiology_studies
Limits:
Humans
Language:
Zh
Journal:
Acta Academiae Medicinae Sinicae
Year:
2019
Type:
Article