Advances in the Apoptosis Repressor with Caspase Recruitment Domain in Cardiovascular Diseases / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 536-540, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-775998
ABSTRACT
Apoptosis plays important roles in maintaining normal development and homeostasis and in the pathophysiological processes of various diseases.Previous studies have shown that cardiomyocyte apoptosis is involved in the development of various cardiovascular diseases.The apoptosis repressor with caspase recruitment domain(ARC)is abundantly expressed in heart,which makes ARC a unique and central cardioprotective factor via anti-apoptotic pathway.This article reviews the structure and characteristics of ARC as well as the roles and mechanisms of ARC in cardiovascular diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Cardiovascular Diseases
/
Apoptosis
/
Apoptosis Regulatory Proteins
/
Caspase Activation and Recruitment Domain
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2019
Type:
Article
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