Analysis of hematological phenotype and genotype of Hb Q-Thailand in Fujian area / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 761-764, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-776812
ABSTRACT
OBJECTIVE@#To explore the hematological phenotype and genotype of hemoglobin Q-Thailand in Fujian area.@*METHODS@#Genomic DNA was extracted from peripheral venous blood samples of patients. Suspected samples were screened by hematological parameters analysis and verified with DNA sequencing.@*RESULTS@#In 35 patients suspected with Hb Q-Thailand, 20 were confirmed, which included one case compounded with heterozygous β mutation and one compounded with Hb New York.@*CONCLUSION@#Analysis of hematological phenotype and genotype of Hb Q-Thailand can faciliate genetic counseling for patients from Fujian area.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Hemoglobins, Abnormal
/
China
/
Genetics
/
Genotype
/
Heterozygote
/
Mutation
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2019
Type:
Article
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