Clinics in diagnostic imaging (193). Sporadic Creutzfeldt-Jakob disease (sCJD)
Singapore medical journal
;
: 634-641, 2018.
Article
in English
| WPRIM
| ID: wpr-776979
ABSTRACT
A 68-year-old man presented with a three-week history of rapidly progressive dementia, gait ataxia and myoclonus. Subsequent electroencephalography showed periodic sharp wave complexes, and cerebrospinal fluid assay revealed the presence of a 14-3-3 protein. A probable diagnosis of sporadic Creutzfeldt-Jakob disease was made, which was further supported by magnetic resonance (MR) imaging of the brain showing asymmetric signal abnormality in the cerebral cortices and basal ganglia. The aetiology, clinical features, diagnostic criteria, various MR imaging patterns and radiologic differential diagnosis of sporadic Creutzfeldt-Jakob disease are discussed in this article.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Brain
/
Diagnostic Imaging
/
Cerebral Cortex
/
Cerebrospinal Fluid
/
Creutzfeldt-Jakob Syndrome
/
Prion Diseases
/
Hypoxia-Ischemia, Brain
/
Dementia
/
Diffusion Magnetic Resonance Imaging
Type of study:
Diagnostic study
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Singapore medical journal
Year:
2018
Type:
Article
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