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Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury / 神经科学通报·英文版
Neuroscience Bulletin ; (6): 639-646, 2018.
Article in English | WPRIM | ID: wpr-777007
ABSTRACT
Prognostication of coma patients after brain injury is important, yet challenging. In this study, we evaluated the predictive value of amplitude-integrated electroencephalography (aEEG) for neurological outcomes in coma patients. From January 2013 to January 2016, 128 coma patients after acute brain injury were prospectively enrolled and monitored with aEEG. The 6-month neurological outcome was evaluated using the Cerebral Performance Category Scale. aEEG monitoring commenced at a median of 7.5 days after coma onset. Continuous normal voltage predicted a good 6-month neurological outcome with a sensitivity of 93.6% and specificity of 85.2%. In contrast, continuous extremely low voltage, burst-suppression, or a flat tracing was correlated with poor 6-month neurological outcome with a sensitivity of 76.5% and specificity of 100%. In conclusion, aEEG is a promising predictor of 6-month neurological outcome for coma patients after acute brain injury.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Severity of Illness Index / Brain / Brain Injuries / Prospective Studies / Follow-Up Studies / Sensitivity and Specificity / Coma / Diagnosis / Electroencephalography Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Limits: Female / Humans / Male Language: English Journal: Neuroscience Bulletin Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Severity of Illness Index / Brain / Brain Injuries / Prospective Studies / Follow-Up Studies / Sensitivity and Specificity / Coma / Diagnosis / Electroencephalography Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Limits: Female / Humans / Male Language: English Journal: Neuroscience Bulletin Year: 2018 Type: Article