Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 639-646, 2018.
Article
in English
| WPRIM
| ID: wpr-777007
ABSTRACT
Prognostication of coma patients after brain injury is important, yet challenging. In this study, we evaluated the predictive value of amplitude-integrated electroencephalography (aEEG) for neurological outcomes in coma patients. From January 2013 to January 2016, 128 coma patients after acute brain injury were prospectively enrolled and monitored with aEEG. The 6-month neurological outcome was evaluated using the Cerebral Performance Category Scale. aEEG monitoring commenced at a median of 7.5 days after coma onset. Continuous normal voltage predicted a good 6-month neurological outcome with a sensitivity of 93.6% and specificity of 85.2%. In contrast, continuous extremely low voltage, burst-suppression, or a flat tracing was correlated with poor 6-month neurological outcome with a sensitivity of 76.5% and specificity of 100%. In conclusion, aEEG is a promising predictor of 6-month neurological outcome for coma patients after acute brain injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Severity of Illness Index
/
Brain
/
Brain Injuries
/
Prospective Studies
/
Follow-Up Studies
/
Sensitivity and Specificity
/
Coma
/
Diagnosis
/
Electroencephalography
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Neuroscience Bulletin
Year:
2018
Type:
Article
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