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Facilitative glucose transporters: expression, distribution and the relationship to diseases / 生理学报
Acta Physiologica Sinica ; (6): 350-360, 2019.
Article in Chinese | WPRIM | ID: wpr-777179
Responsible library: WPRO
ABSTRACT
Facilitative glucose transporters (GLUT) are proteins that mediate glucose transmembrane transport in the form of facilitated diffusion, which play an important role in regulating cell energy metabolism. There are many breakthroughs in researches of facilitative GLUT in recent years. It has been known that there are 14 subtypes of facilitative GLUT with obvious tissue specificity in distribution and physiological function. In the present review, the tissue and cellular distribution, subcellular localization, expression regulation, physiological function and the relationship to diseases of facilitative GLUT subtypes were summarized, in order to further understand their physiological and pathophysiological significances.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Biological Transport / Humans / Disease / Energy Metabolism / Glucose Transport Proteins, Facilitative / Glucose Language: Chinese Journal: Acta Physiologica Sinica Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Biological Transport / Humans / Disease / Energy Metabolism / Glucose Transport Proteins, Facilitative / Glucose Language: Chinese Journal: Acta Physiologica Sinica Year: 2019 Type: Article