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Review of the mechanism of biomimetic intrafibrillar mineralization / 口腔疾病防治
Article in Chinese | WPRIM | ID: wpr-777781
Responsible library: WPRO
ABSTRACT
@#Bone is a hierarchically structured and highly mineralized hard tissue composed of an organic phase (type I collagen and noncollagenous proteins) and an inorganic phase (nanohydroxyapatite). Intrafibrillar mineralized collagen is the basic structural unit of bone tissue and is of high significance due to its superior mechanical and biological properties. Thus, to truly understand the unique properties of bone, it is necessary to review the most basic structural level of bone. In this article, we review the recent advances in understanding the development of intrafibrillar mineralization and the prevailing theories in the formation of such intrafibrillar minerals. Understanding the mechanisms of intrafibrillar mineralization may facilitate the development of engineered bone for clinical applications and provide deeper insight into the nature of biomineralization.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Prevention and Treatment for Stomatological Diseases Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Prevention and Treatment for Stomatological Diseases Year: 2018 Type: Article