microRNAs in corneal neovascularization / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#Corneal avascularity is critical for its immune privilege and optical transparency. It remains avascular in spite of being surrounded by vessel-enriched conjunctiva. The endogenous angiogenesis inhibitors are responsible to the cornea's avascularity.MicroRNAs(miRs)are a class of endogenous small non-coding RNAs. Some miRs, such as miR-184, 204, and 21, are involved in the process of corneal neovascularization. In this article, we summarized the studies of miRs related to corneal neovascularization in order to provide a useful guidance for future therapy and research.