Differences in the clinicopathological features of pancreatic head carcinoma arising from the dorsal pancreas and the ventral pancreas / 临床肝胆病杂志

ABSTRACT

The pancreas arises from the dorsal and ventral anlagen. The dorsal anlagen forms the cephalic part of the head of the pancreas, the neck of the pancreas, the body of the pancreas, and the tail of the pancreas, while the ventral anlagen forms the caudal part of the head of the pancreas and the uncinate process of the pancreas. There is a fusion plane between the dorsal pancreas and the ventral pancreas, which can be identified by immunohistochemical staining of pancreatic polypeptide. There are differences in local invasion, lymph node metastasis, neural invasion, and survival time between pancreatic head carcinoma arising from the dorsal pancreas and that arising from the ventral pancreas. This article reviews the differences in clinicopathological features between these two types of pancreatic head carcinoma.