A Case of Disseminated Penicillium marneffei Infection in a Liver Transplant Recipient / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 400-405, 2010.
Article
in Korean
| WPRIM
| ID: wpr-77835
ABSTRACT
Penicillium marneffei is the only dimorphic fungus among Penicillium spp. that can cause a fatal infection in immunocompromised patients. P. marneffei is endemic in Southeast Asia and eastern China. P. marneffei infection is an AIDS-defining illness and the third most common opportunistic infection in the endemic regions. Here, the authors report a case of disseminated P. marneffei infection in a patient who underwent liver transplantation in China. During the hospital stay, the mold form of the fungus that produced a red wine-colored pigment on the agar plate was isolated from the patient's urine, transtracheal aspirate, and blood. The fungus was identified as P. marneffei by direct sequencing of the D1-D2 and ITS regions. Thermal dimorphism was also confirmed by subculturing the colony at 37degrees C. To the best of our knowledge, this is the first Korean case of disseminated P. marneffei infection in a liver transplant recipient.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Penicillium
/
Liver Transplantation
/
Immunocompromised Host
/
Sequence Analysis, DNA
/
Liver Cirrhosis
/
Mycoses
Type of study:
Prognostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2010
Type:
Article
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