Research advances in diagnosis and treatment of IgG4-associated autoimmune hepatitis / 临床肝胆病杂志

ABSTRACT

Autoimmune hepatitis (AIH) is a chronic progressive inflammatory disease involving the liver parenchyma. In recent years, there have been more studies focusing on IgG4-associated diseases. Foreign scholars have found that patients with AIH also have IgG4-positive plasma cell infiltration in the liver, suggesting that IgG4 may be involved in the pathogenesis of AIH, and this disease is considered a special type of AIH and thus it is called IgG4-associated AIH (IgG4-AIH). This article reviews the research advances in the diagnosis and treatment of AIH and IgG4-AIH, so as to enhance clinical doctors′knowledge of such diseases.