Advances in the diagnosis and treatment of severe acute cholangitis / 临床肝胆病杂志

ABSTRACT

Severe acute cholangitis, also called acute obstructive suppurative cholangitis (AOSC), has acute onset and rapid progression and is the primary cause of death in patients with benign biliary tract diseases, especially in elderly patients, and it is often complicated by multiple system organ failure. This disease has diversified symptoms and signs, which leads to the inconsistency in diagnostic grading and prognosis criteria. With the development of minimally invasive surgery and endoscopic techniques, the diagnosis and treatment of severe acute cholangitis has been constantly improved. Therefore, judgment and selection of the optimal surgical timing, individualized biliary drainage, and comprehensive, standardized, and timely anti-infective therapy based on prognostic factors have great importance in the treatment of severe acute cholangitis.