Role of NLRP3 inflammasome in the development and progression of liver diseases / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 2346-2350, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-778749
ABSTRACT
Immune cascade due to inflammasome has become a research hotspot in recent years, and the role of NLRP3 inflammasome in the development and progression of liver diseases has attracted more and more attention. This article analyzes the action characteristics and regulatory mechanism of NLRP3 inflammasome in liver diseases, such as viral hepatitis, liver fibrosis, nonalcoholic fatty liver disease, liver failure, and liver cancer, and establishes targeted therapy based on NLRP3 inflammasome to regulate immune response triggered by inflammasome, in order to provide new ideas for the prevention and treatment of liver diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2019
Type:
Article
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