Mechanism of action of protein phosphatase 2A in the promotion and inhibition of hepatocellular carcinoma / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 1123-1128, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-778773
ABSTRACT
Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase involved in many signaling pathways associated with cell growth and proliferation, and it also regulates many cellular processes. With an in-depth exploration of PP2A in the process of cell activity, especially malignant tumors, the association between PP2A and hepatocellular carcinoma (HCC) has attracted more and more attention in recent years; however, there is still a controversy over whether PP2A can promote or inhibit HCC. This article reviews the research advances in the mechanism of action of PP2A as a tumor factor in the regulation of HCC and target therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2019
Type:
Article
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