Nonsurgical treatment of malignant biliary obstructive diseases / 临床肝胆病杂志

ABSTRACT

Malignant biliary obstructive diseases are caused by various primary or metastatic malignancies of the liver, the biliary tract, and the pancreas, with major clinical manifestations of obstructive jaundice, liver impairment, and cholangitis. Early diagnosis of such patients is difficult, and most patients are in an advanced stage at the time of diagnosis and lose the opportunity for surgical resection. Nonsurgical treatment techniques including biliary drainage and biliary stent implantation play an important role in palliative treatment of patients with unresectable malignant biliary obstructive diseases. The application of new techniques, such as biliary radiofrequency ablation, intraductal brachytherapy, and photodynamic therapy, further promotes the improvement in the effect of nonsurgical treatment methods including biliary drainage. With the help of related research advances, these techniques can be applied in clinical practice in a standardized way.