Research advances in gut microbiota in liver cirrhosis and related complications / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 2433-2437, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-778961
ABSTRACT
Liver cirrhosis is an end-stage fibrotic disease of chronic liver injury induced by various factors. Many studies have shown that gut microbiota (GM) are involved in the development and progression of liver cirrhosis and related complications, such as portal hypertension, hepatic encephalopathy, spontaneous bacterial peritonitis, and hepatocellular carcinoma. In addition, impaired intestinal barrier, compromised liver immunity, and bacterial translocation play a critical role in the progression of liver cirrhosis. This article summarizes the role of GM in liver cirrhosis and related complications and research advances and problems in GM as a therapeutic target, in order to provide new thoughts for clinical diagnosis and treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS