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Diagnosis, treatment, and prevention of postcholecystectomy syndrome / 临床肝胆病杂志
Journal of Clinical Hepatology ; (12): 2464-2468, 2018.
Article in Chinese | WPRIM | ID: wpr-778967
ABSTRACT
Postcholecystectomy syndrome (PCS) is a common syndrome with complex etiologies after laparoscopic cholecystectomy, rather than a specific disease. In addition to bile duct stones, bile duct injury, and sphincter of Oddi dysfunction, PCS is also associated with the abnormalities in bile acid pool, farnesoid X receptor, and GPBAR1/TGR5 pathways after surgery, reductions in fibroblast growth factor 19 and surfactant protein D, changes in gastrointestinal hormones such as motilin and cholecystokinin, and disappearance of various physiological reflexes and nerve reflexes involving the gallbladder. All these changes in physiological function can induce PCS. As the number of patients undergoing laparoscopic cholecystectomy is increasing year by year, the incidence rate of PCS is also increasing. This article briefly summarizes the etiology, pathophysiology, diagnosis, treatment, and prevention of PCS.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Journal of Clinical Hepatology Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Journal of Clinical Hepatology Year: 2018 Type: Article