Advances in research hotspots in liver failure complicated by acute kidney injury / 临床肝胆病杂志

ABSTRACT

Acute kidney injury (AKI) is defined as a sharp drop in glomerular filtration rate (GFR) and a rapid increase in serum creatinine and is one of the most serious complications of liver failure. Early diagnosis and treatment play a vital role in reducing the mortality and improving the prognosis of liver failure. This article elaborates on the research advances in the diagnostic criteria, pathogenesis, biomarkers, clinical features, and treatment of AKI and points out that constant modification of the definition and staging of AKI and research and development of efficient biomarkers for AKI are future research directions.