Role of intestinal microflora in the pathogenesis of hepatocellular carcinoma / 临床肝胆病杂志

ABSTRACT

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and is one of the complications of chronic liver diseases. Recent experimental and clinical studies have shown that the gut-liver axis plays a key role in the pathogenesis of chronic liver diseases including HCC. Change in intestinal microflora is considered the key factor for the progression of chronic liver diseases to HCC. This article summarizes the latest research advances in changes in intestinal microflora associated with HCC and discusses the importance of intestinal microflora in the development and progression of HCC.