Pathogenesis of immunoglobulin G4-related hepatobiliary and pancreatic diseases / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 1401-1405, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-779124
ABSTRACT
Immunoglobulin G4 (IgG4)-related disease is a chronic progressive autoimmune disease involving multiple systems throughout the body. IgG4-related hepatobiliary and pancreatic diseases are the manifestation of IgG4-related disease involving the hepatobiliary and pancreatic systems, with the main features of an increased serum IgG4 level and IgG4-positive lymphoplasmacytic infiltration. IgG4-related hepatobiliary and pancreatic diseases can mimic various inflammations and tumor diseases, which may lead to missed diagnosis and misdiagnosis in clinical practice. This article elaborates on the pathogenesis of IgG4-related hepatobiliary and pancreatic diseases from the perspectives of genetic inheritance, infection and molecular mimicry, and immune factors, so as to improve the understanding of such diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2019
Type:
Article
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