Dose-response relationship between light at night and nonalcoholic fatty liver in steel workers / 中华疾病控制杂志
Chinese Journal of Disease Control & Prevention
;
(12): 1353-1357,1363, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-779520
ABSTRACT
Objective To explore the relationship between light at night (LAN) and nonalcoholic fatty liver (NAFLD) in steel workers. Methods Relevant information was collected through questionnaires, physical examinations and blood biochemical analysis. Using restricted cubic spline (RCS) and mutiple Logistic regression model to explore the relationship between LAN and NAFLD based on a cross-sectional study. Results The prevalence of NAFLD was 33.8% (2 594 / 7 664) in steel workers. After adjusting for age, sex, marriage, educational level, smoking, drinking, body mass index, luminous intensity in life, liver enzyme metabolism, blood lipid level, physical activity, diet, sleep duration, shift work, high temperature, noise, dust, and carbon monoxide exposure, the RCS model showed a nonlinear dose-response relationship between LAN and NAFLD ( 2=71.59, P<0.001 for overall association test and 2=16.92, P<0.001 for nonlinear test); Multivariate Logistic regression model showed that after adjusting for all confounding factors, when the LAN in the 1 178 d ~ 2 017 d and 2 017 d ~ group, the prevalence of NAFLD increased by 21.7% (OR=1.217, 95% CI 1.027-1.441) and 47.9% (OR=1.479, 95% CI 1.240-1.763), respectively, when compared with the group LAN<1 178 d. Conclusion There is a nonlinear dose-response relationship between LAN and NAFLD in steel works.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Disease Control & Prevention
Year:
2019
Type:
Article
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