Interleukin-1β is a potential therapeutic target for periodontitis: a narrative review / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 2-2, 2020.
Article
in English
| WPRIM
| ID: wpr-781380
ABSTRACT
Interleukin(IL)-1β, a pro-inflammatory cytokine, was elevated and participates in periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical evidence, but also the increased IL-1β triggers a series of inflammatory reactions and promotes bone resorption. Currently, IL-1β blockage has been therapeutic strategies for autoimmune and autoinflammatory diseases such as rheumatoid arthritis, cryopyrin-associated periodic syndromes, gout and type II diabetes mellitus. It is speculated that IL-1β be a potential therapeutic target for periodontitis. The review focuses on the production, mechanism, present treatments and future potential strategies for IL-1β in periodontitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
International Journal of Oral Science
Year:
2020
Type:
Article
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