A Case of Cytomegalovirus Pneumonia in a Healthy Infant / 소아알레르기및호흡기학회지

ABSTRACT

CMV is a largest member of herpes viridae consisted of 230-240 Kb double stranded DNA, 20 protein matrix and envelope. It has specific replication cycle with 3 phase. Human immunity against CMV, cellular immune and humoral immune are envolved and specially CD + 8 cytotoxic cell and natural killer cell are important because they controll primary infection, recurrent infection and latent infection. Our patient was 2 month old, healthy female infant. She had acute pneumonia and then progressed fulminent respiratory failure, cardiomegaly, hydrocephalus and DIC. At first, we tried to find cause of this condition but couldn't anything. We performed several CMV serologic study and on hospital day 30th, Anti-CMV IgM was positive and increased IgG. And we report the case of CMV pneumonia in a healthy infant.