Autoimmune Hepatic Failure Following Acute Hepatitis A is Accompanied by Inflammatory Conversion of Regulatory T Cells
Yonsei Medical Journal
;
: 100-102, 2020.
Article
in English
| WPRIM
| ID: wpr-782117
ABSTRACT
autoimmune hepatitis (AIH) following acute hepatitis A (AHA) in immunologic aspects, we performed multi-color flow cytometry with peripheral blood mononuclear cells of a patient who underwent liver transplantation due to AIH-induced liver failure. Unlike general AHA patients, the proportion of tumor necrosis factor-α-producing Treg cells remained high for 6 months after diagnosis of AHA until she underwent a liver transplantation. The conversion of Treg cells into mediators of inflammation may have played a role in the autoimmune pathogenesis following AHA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Liver Transplantation
/
Liver Failure
/
T-Lymphocytes, Regulatory
/
Inflammation Mediators
/
Hepatitis, Autoimmune
/
Diagnosis
/
Flow Cytometry
/
Hepatitis
/
Hepatitis A
/
Necrosis
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
2020
Type:
Article
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