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Update on the Management of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity
Yonsei Medical Journal ; : 4-14, 2020.
Article in English | WPRIM | ID: wpr-782129
ABSTRACT
phenotypes of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity are heterogeneous with various presentations including time of symptom onset, organ involvements, and underlying pathophysiology. Having a correct diagnosis can be challenging. Understanding their respective mechanisms as well as developing a comprehensive classification and diagnostic algorithm are pivotal for appropriate management strategy. Treatment modalities are based on the subtypes and severity of hypersensitivity reactions. Insights into the phenotypes and endotypes of hypersensitivity reactions enable personalized management in patients with suboptimal control of disease. This review updated the recent evidence of pathophysiology, classification, diagnostic algorithm, and management of NSAID hypersensitivity reactions.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Phenotype / Asthma / Urticaria / Rhinitis / Classification / Diagnosis / Drug Hypersensitivity / Hypersensitivity / Angioedema Type of study: Diagnostic study Limits: Humans Language: English Journal: Yonsei Medical Journal Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Phenotype / Asthma / Urticaria / Rhinitis / Classification / Diagnosis / Drug Hypersensitivity / Hypersensitivity / Angioedema Type of study: Diagnostic study Limits: Humans Language: English Journal: Yonsei Medical Journal Year: 2020 Type: Article