Potential predictors for chemotherapeutic response and prognosis in epithelial ovarian, fallopian tube and primary peritoneal cancer patients treated with platinum-based chemotherapy
Obstetrics & Gynecology Science
;
: 55-63, 2020.
Article
in English
| WPRIM
| ID: wpr-782209
ABSTRACT
3.38, PLR >210, CA125 >365, advanced stage, suboptimal disease, serous type, and ascites were significant predictive factors for platinum resistance. However, only NLR >3.38 and advanced stage were independent predictive factors with an adjusted odds ratio of 1.880 and 3.333, respectively. Regarding factors associated with poor survival outcomes, only PLR >210 and advanced stage were independent factors, with a hazard ratio of 1.578 and 3.994, respectively.CONCLUSION:
High NLR and advanced stage were potential independent predictive factors for platinum resistance, whereas high PLR and advanced stage were potential independent predictive factors for poor survival outcomes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Neoplasms
/
Platinum
/
Prognosis
/
Ascites
/
Blood Platelets
/
Lymphocytes
/
Odds Ratio
/
Medical Records
/
Multivariate Analysis
/
Retrospective Studies
Type of study:
Etiology study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2020
Type:
Article
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