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Endoscopic Findings and Clinical Significance of Portal Hypertensive Colopathy / 대한소화기학회지
Article in Ko | WPRIM | ID: wpr-78286
Responsible library: WPRO
ABSTRACT
BACKGROUND/AIMS: The endoscopic findings and clinical relevance of portal hypertensive colopathy are not well described in Korea. We aimed to do a retrospective study of mucosal changes in the colon of patients with liver cirrhosis and to find their association with clinical characteristics. METHODS: We reviewed the clinical data and endoscopic findings of 48 patients with liver cirrhosis and 48 patients, matched for age and sex, with irritable bowel disease (IBS) who underwent colonoscopy over a 5 year span. RESULTS: Patients with liver cirrhosis were more likely to have colitis-like lesions and vascular abnormalities than IBS patients. Low platelet count (p=0.005) and severe esophageal varices (p=0.011) were associated with portal hypertensive colopathy, whereas the etiologies and severity of cirrhosis were not associated with these findings. CONCLUSIONS: Portal hypertensive colopathy can be defined with colitis-like lesions or vascular lesions. These lesions are more frequently present in patients with more severe esophageal varices and thrombocytopenia.
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Full text: 1 Index: WPRIM Main subject: Platelet Count / Thrombocytopenia / Severity of Illness Index / Esophageal and Gastric Varices / Retrospective Studies / Colonoscopy / Irritable Bowel Syndrome / Hypertension, Portal / Intestinal Mucosa / Liver Cirrhosis Type of study: Diagnostic_studies / Observational_studies Limits: Adult / Aged / Female / Humans / Male Language: Ko Journal: The Korean Journal of Gastroenterology Year: 2011 Type: Article
Full text: 1 Index: WPRIM Main subject: Platelet Count / Thrombocytopenia / Severity of Illness Index / Esophageal and Gastric Varices / Retrospective Studies / Colonoscopy / Irritable Bowel Syndrome / Hypertension, Portal / Intestinal Mucosa / Liver Cirrhosis Type of study: Diagnostic_studies / Observational_studies Limits: Adult / Aged / Female / Humans / Male Language: Ko Journal: The Korean Journal of Gastroenterology Year: 2011 Type: Article