Influence of Stomach Cancer Risk Factors on the Development of Gastric Dysplasia
Korean Journal of Health Promotion
;
: 177-183, 2011.
Article
in English
| WPRIM
| ID: wpr-78300
ABSTRACT
BACKGROUND:
Both atrophic gastritis and intestinal metaplasia may progress to gastric dysplasia. This study aimed to analyze the factors influencing progression of atrophic gastritis and intestinal metaplasia to dysplasia.METHODS:
People diagnosed with atrophic gastritis and intestinal metaplasia for the first time received a follow-up endoscopy and were investigated for the cumulative incidence rate of gastric dysplasia by age, gender, smoking habit, alcohol intake, rice consumption and family history of stomach cancer.RESULTS:
The cumulative incidence rate increased with age, consuming > or =3 bowls of rice per day and family history of stomach cancer. Multivariate analysis showed that the cumulative incidence rate of gastric dysplasia increased in subjects >61 years (RR=2.54, P=0.014), in those consuming > or =3 bowls of rice per day (RR=1.46, P=0.021) and in those with a family history of stomach cancer (RR=1.31, P=0.037).CONCLUSIONS:
More active management, such as intensive endoscopic follow-up examinations, lifestyle change and education regarding gastric dysplasia, are required in those older than 61 years, having a higher intake of grain or with a family history of stomach cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Stomach
/
Stomach Neoplasms
/
Smoking
/
Edible Grain
/
Incidence
/
Multivariate Analysis
/
Risk Factors
/
Follow-Up Studies
/
Endoscopy
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Korean Journal of Health Promotion
Year:
2011
Type:
Article
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