Retrospective Analysis of the Natural History of Atopic Dermatitis Occurring in the First Year of Life in Korean Children
Journal of Korean Medical Science
;
: 723-728, 2012.
Article
in English
| WPRIM
| ID: wpr-7841
ABSTRACT
The aim of this study was to analyze the natural history of atopic dermatitis (AD) and the risk factors associated with the remission of AD in Korean children. We enrolled 597 children with AD that occurred in the first year of life. A variety of factors influencing the prognosis were assessed by medical records and telephone interviews. Their outcome was classified into complete remission, intermittent, and persistent AD. AD had completely disappeared in 422 cases (70.6%), while 149 (25%) and 26 cases (4.4%) showed intermittent and persistent skin symptoms, respectively. The average healing time was 29.6 months in complete remission group and expected healing time of the AD was 60 months. None of risk factors were significant by multivariate analysis. But, in moderate-to-severe AD group, maternal diet restriction during lactation (P = 0.046) and no sensitization to cow's milk (P = 0.017) were significantly associated with remission of AD in the multivariate analysis. In conclusion, AD occurring in the first year of life disappears in a significant proportion of patients. In addition, in Korean children with moderate-to-severe AD, maternal diet restriction of allergenic food during lactation and sensitization to cow's milk seem to predict the prognosis of AD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Remission Induction
/
Lactation
/
Interviews as Topic
/
Predictive Value of Tests
/
Retrospective Studies
/
Risk Factors
/
Milk Hypersensitivity
/
Dermatitis, Atopic
/
Republic of Korea
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Qualitative research
/
Risk factors
Limits:
Adult
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2012
Type:
Article
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