CLINICAL AND STATISTICAL ANALYSIS OF THE ORAL CANCER PATIENTS : A STATISTICAL ANALYSIS OF 256 CASES

ABSTRACT

hospital charts of 256 consecutive patients who had been diagnosed malignant tumor at the Department of Oral and Maxillofacial surgery, Kyung-Pook University Hospital between 1962 and 1996. Following results were obtained. 1. The histologic diagnosis of oral cancer was mostly squamous cell carcinoma(78.1%) followed by adenoid cystic carcinoma(5.9%), malignant melanoma(3.5%), mucoepidermoid carcinoma(3.1%), osteosarcoma(2.7%), metastatic carcinoma(2.3%). 2. The primary sites were the lower alveolus and gingiva(21.8%), upper alveolus and gingiva(19.5%), mouth floor(17.6%), tongue(1.5%), palate(9.8%), maxillary sinus(7.4%), retromolar trigone(6.6%), buccal mucosa(3.9%), major salivary gland(2.0%), upper lip(0.45) and lower lip(0.45). 3. Males were involved more than females by oral cancer in the ratio of 2.51, especially squamous cell carcinoma in the ratio of 3.31. 4. Most of the case occurred in the 6th and 7th decades(58.%), and average age was 58. 5. The common symptoms were pain followed by swelling, ulcer, bleeding, pus discharge, trismus, paresthesia, pigmentation, paralysis. 6. Time lapse from the recognition of initial symptoms to the first visit was mostly less than 3 months. 7. According to TNM system in squamous cell carcinoma, stage IV(61.3%) was most frequent, followed by stage II(14.1%), stage I(12.7%), stage III(12.0%). 8. The degree of histopathological differentiation of oral squamous cell carcinoma was in the order of well, moderate, poor differentiated type. 9. In the treatment of squamous cell carcinoma, surgery was done in the 75 cases, and neck dissection in 58 cases. 10. 5-year survival rate of the patient treatment between 1982 and 1990, was 31.6%, 5-year survival rate of the patients treated between 1991 and 1996, was 54%.