Vascular effects of the inferior alveolar nerve injection of 2% lidocaine hci with 1:100,000 epinephrine

ABSTRACT

tongue following inferior alveolar nerve block of 2% lidocaine HCl with 1100,000 epinephrine. Twenty-two rats were randomly allocated to three groups control group; without mandibular nerve block, experimental group 1; 2% lidocaine HCl, experimental group 2; 2% lidocaine HCl plus 1100,000 epinephrine. The assessments were performed at 1-, 5-, 30-, 60-, 120-minute after inferior alveolar nerve block. Vessel diameters using the micrometer were measured and compared. Results showed that the increase in vascular constriction in group 3 was greater than those in groups 1 and 2. In conclusion, local anesthesia combined with epinephrine assures safer anesthesia for hemostasis.