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Effect of Electron-beam Irradiaton on the Artificial Bone Substitutes Composed of Hydroxyapatite and Tricalcium Phosphate Mixtures with Type I Collagen
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons ; : 38-50, 2013.
Article in Korean | WPRIM | ID: wpr-785197
ABSTRACT
PURPOSE: The aim of this study is to evaluate the effect and potential of electron beam (E-beam) irradiation treatment to the synthetic bony mixtures composed of hydroxyapatite (HA; Bongros(R), Bio@ Co., Korea) and tricalcium phosphate (beta-TCP, Sigma-Aldrich Co., USA), mixed at various ratios and of type I collagen (Rat tail, BD Biosciences Co., Sweden) as an organic matrix.

METHODS:

We used 1.0~2.0 MeV linear accelerator and 2.0 MeV superconductive linear accelerator (power 100 KW, pressure 115 kPa, temperature -30~120degrees C, sensor sensitivity 0.1~1.2 mV/kPa, generating power sensitivity 44.75 mV/kPa, supply voltage 5+/-0.25 V) with different irradiation dose, such as 1, 30 and 60 kGy. Structural changes in this synthetic bone material were studied in vitro, by scanning electron microscopy (SEM), elementary analysis and field emission scanning electron microscope (FE-SEM), attenuated total reflection (ATR), and electron spectroscopy for chemical analysis (ESCA).

RESULTS:

The large particular size of HA was changed after E-beam irradiation, to which small particle of TCP was engaged with organic collagen components in SEM findings.

CONCLUSION:

The important new in vitro data to be applicable as the substitutes of artificial bone materials in dental and medical fields will be able to be summarized.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Particle Accelerators / Tail / Bone Regeneration / Calcium Phosphates / Microscopy, Electron, Scanning / Collagen / Durapatite / Bone Substitutes / Collagen Type I / Electrons Language: Korean Journal: Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Particle Accelerators / Tail / Bone Regeneration / Calcium Phosphates / Microscopy, Electron, Scanning / Collagen / Durapatite / Bone Substitutes / Collagen Type I / Electrons Language: Korean Journal: Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons Year: 2013 Type: Article