Estrogen-secreting adrenocortical carcinoma / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 54-58, 2019.
Article
in English
| WPRIM
| ID: wpr-785295
ABSTRACT
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete aldosterone or androgen. Estrogen-secreting adrenocortical carcinomas are extremely rare, irrespective of the secretion status of other adrenocortical hormones. Here, we report the case of a 53-year-old man with a cortisol and estrogen-secreting adrenocortical carcinoma. The patient presented with gynecomastia and abdominal discomfort. Radiological assessment revealed a tumor measuring 21×15.3×12 cm localized to the retroperitoneum. A hormonal evaluation revealed increased levels of estradiol, dehydroepiandrosterone sulfate, and cortisol. The patient underwent a right adrenalectomy, and the pathological examination revealed an adrenocortical carcinoma with a Weiss' score of 6. After surgery, he was treated with adjuvant radiotherapy. Twenty-one months after treatment, the patient remains alive with no evidence of recurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Hydrocortisone
/
Incidence
/
Adrenal Gland Neoplasms
/
Adrenocortical Carcinoma
/
Adrenalectomy
/
Radiotherapy, Adjuvant
/
Dehydroepiandrosterone Sulfate
/
Aldosterone
/
Estradiol
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Yeungnam University Journal of Medicine
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS