Imatinib-induced hepatitis treated by corticosteroids in a patient with metastatic gastrointestinal stromal tumor / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 155-158, 2019.
Article
in English
| WPRIM
| ID: wpr-785305
ABSTRACT
Imatinib mesylate is currently used as the first-line treatment for metastatic gastrointestinal stromal tumors (GISTs). Imatinib-induced hepatotoxicity in patients with GIST is very rare. Its features vary from subclinical elevation of serum aminotransferase to clinically apparent acute hepatitis, which is associated with immunologic reactions. Imatinib-induced hepatotoxicity with autoimmune-like features can be treated by the discontinuation of imatinib mesylate and the administration of oral steroids. Here, we report a case of late-onset imatinib-induced hepatitis with autoimmune-like features in a patient with metastatic GIST, which was improved by oral corticosteroids.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Steroids
/
Adrenal Cortex Hormones
/
Gastrointestinal Stromal Tumors
/
Chemical and Drug Induced Liver Injury
/
Imatinib Mesylate
/
Hepatitis
Limits:
Humans
Language:
English
Journal:
Yeungnam University Journal of Medicine
Year:
2019
Type:
Article
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